Only those medical conditions are considered for which there are 2 or more than 2 statistically significant human studies published in peer-reviewed journals upto the end of year 2010. There are 33 such health conditions. The compendium is prepared by mining 14 online electronic databases.
The term nosode was introduced by Hering. The first nosode psorinum was introduced in 1828. Nosodes constitutes less than 4% of all homeopathic medicines listed in homeopathic pharmacopoeia. Nosodes are not a routine prescription (prescribed infrequently) and are generally prescribed in chronic conditions in 200c potency and above. Use of nosodes and sarcodes in the treatment of disease conditions is known as biotherapy or immunotherapy or organopathy. Upto the end of 2012, there have been 11 research (human) studies including 4 DBRPCT published in 6 peer-reviewed journals (2 integrative, 2 homeopathy and 2 CAM journals) in evidence of 9 nosodes.
Upto the end of year 2010, there have been 53 studies published in 36 peer-reviewed medical journals (29 integrative, 1 homeopathy and 6 CAM journals) including 1 meta-analysis, 1 systematic review and 23 DBRPCT in evidence of combination remedies in homeopathy. These 53 studies on combination remedies are part of the total 299 human studies in evidence of homeopathy upto the end of 2010.