The term nosode was introduced by Hering. The first nosode psorinum was introduced in 1828. Nosodes constitutes less than 4% of all homeopathic medicines listed in homeopathic pharmacopoeia. Nosodes are not a routine prescription (prescribed infrequently) and are generally prescribed in chronic conditions in 200c potency and above. Use of nosodes and sarcodes in the treatment of disease conditions is known as biotherapy or immunotherapy or organopathy. Upto the end of 2012, there have been 11 research (human) studies including 4 DBRPCT published in 6 peer-reviewed journals (2 integrative, 2 homeopathy and 2 CAM journals) in evidence of 9 nosodes.
Nosodes: Medicines prepared from inactivated disease products of human, animal or vegetable origin or cultures of micro-organisms (bacteria, virus, fungi) are known as Nosode.
Auto-nosodes: Nosodes prepared frompatient’s own body are known as auto-nosodes.
Isodes: Medicines prepared from
identicaldisease product are called isodes
Treatment of disease by high potency of Isodes is known as Isopathy.
Isopathy was introduced in 1833 by Johann Joseph Wilhelm Lux, Professor of Veterinary Medicine, University of Leipzig, Germany.
Auto-Isodes: Isodesprepared frompatient’s own body are known as auto-isodes.
Treatment of disease by auto-isodes is known as auto-isopathy.
Safety Profile of Nosodes
The source material of a human nosode is verified for the absence of infection. The source material is heated in saturated steam for 20 minutes at a temperature of 133 degree centigrade to make it sterile and further processed (autoclaving) to ensure micro-biological safety .
The source material of an animal nosode has been verified by Pasteur Institute, Paris and found out to be safe for human consumption .
Nosodes are prescribed in the following conditions:
1. Nosode as anti-miasmatic remedy
2. Nosode as an inter-current remedy
3. When-well indicated remedy fails to give relief
4. Nosode as preventive medicine for infectious disease (homeopathic vaccines). Nosodes increases specific immunity regarding definite etiological agents
Now you can attempt a quiz/survey on nosode
The first research study in evidence of nosodes was published in 1964. The research gained momentum when a DBRPCT on nosodeOscillococcusfor treatment of influenza was published in British Journal of Clinical Pharmacology in 1989.
URL Links to 11 studies (Journal-wise) including 6 FULL TEXT papers are available as compendium on this webpage. The compendium is prepared by mining 14 online electronic databases. The studies are also available as PDF which can be viewed at or downloaded fromGoogle Drive
1. Studies on Plants and Animals
2. Studies published in non-journal paper
3.Non-peer reviewed studies from year 1893 onwards
4.Statistically non-significant studies (Probability value<0.05, odds ratio >1, indicates statistical significance)
5.Studies in which combination of homeopathic medicine with any other medicine is prescribed
6.Studies in which medicine is perceived to be homeopathic but is not such as radionically prepared or different potencies of same medicine mixed together
BASIC FUNDAMENTAL RESEARCH
1. Evidence-based Complimentary & Alternative Medicine
Dynamized Preparations in Cell Culture(2009) FULL TEXT //Carcinosinum 200C, Conium, Lycopodium activates beneficial gene p53 which provides defense against tumour/cancer
DOUBLE-BLIND RANDOMISED PLACEBO-CONTROLLED TRIAL
Oscillococcinum in the treatment of influenza(1989) FULL TEXT //(n=487, 237 treated and 241 on placebo), if taken twice daily for 5 days significantly increased the rate of cure within two days, absence of symptoms at 48 hours, relative risk estimate significantly favour homeopathy (p=0.048), no pain and no fever (p=0.048), recovery rate (headache, stiffness, articular pain, shivering reduction) at 48 hours better in homeopathy group (p=0.032)
2.British Homoeopathic Journal
Oscillococcinum in patients with influenza(1998) FULL TEXT // n=372,3 doses per day for 3 days, no spinal pain at 48 hours (p=0.03), no muscle pain at 48 hours (p=0.01), no articulate pain at 48 hours (p=0.009), Significant effect of homeopathy over placebo in influenza (p=0.0257)
3. International Journal of Oncology
Cytotoxic effects of ultra-diluted remedies on breast cancer cells(2010) FULL TEXT //in-vitro study: Carcinosin 30c, Phytolacca Decandra 200c, Conium 3c and Thuja 30c caused death of 5000 breast cancer cell lines in the laboratory for periods of between 1 to 4 days (experiment repeated 3 times), similar to the effect of chemotherapy, but without affecting normal cells. Carcinosin and Phytolacca—achieved up to an 80% response indicating that they caused cancer cell death. By comparison, placebo solvent achieved only 30%. The effects of Carcinosin and Phytolacca were as powerful as Paclitaxel (Taxol)
Application of 200c potency of bacteria for Leptospirosis epidemic control(2010) FULL TEXT //2.3 million people in Cuba given two doses each (7-9 days apart) for protection against Leptospirosis (fever+jaundice+ inflammation in kidney+enlargement of spleen) with only 10 reported cases. Dramatic decrease in morbidity within two weeks and zero morbidity of hospitalised patients. Cost of homeopathic immunization =1/15th of conmed vaccine.
1. The British Homeopathic Journal
Quadruple nosode (Bacillinum, Influenzinum, Pneumococcus and Streptococcus) as a preventive for respiratory infections(1964) // combination remedy
Evaluation of 2LHERP in preventing recurrences of genital herpes (2000) // combination remedy 2LHERP=homeopathic RNA+homeopathic viral DNA
2. International Journal of High Dilution Research
Tuberculinum, Apis, Arsenicum album and sarcodes forNephrotic Syndrome in adults(2009) FULL TEXT
4. Evidence-based Complimentary & Alternative Medicine
5. The Journal of Alternative and Complementary Medicine
 Nosodes in Homeopathy: Significance and Safe, Position Paper, European Coalition of Homeopathic and Anthroposophic Medicnal Products, 2006
 “Evaluation of the viral safety level for the manufacturing process of homeopathic pharmaceutical products from animal origin”, Paster Institiute, Paris,http://www.echamp.eu/fileadmin/user_upload/Positions/Nosodes_in_Homeopathy.pdf
1. Sign the petition to save nosodes in Canada
2. Write to Health Minister of Canada to promote nosodes
Copy the following Format. Edit to your liking and e-mail to Health Minister and others at the following address
CC: email@example.com, firstname.lastname@example.org, email@example.com, firstname.lastname@example.org,email@example.com, firstname.lastname@example.org
Re: Request to Promote Nosodes
Dear Ms. Aglukkaq
I am writing to you to request the Government of Canada to urge the Natural Health Products Directorate (NHPD) of Health Canada to promote natural medicine such as homeopathic system of medicine and homeopathic remedies such as nosodes as they have been medically proved as well as approved by many nations for many decades.
Not only homeopaths and naturopaths but also the national government must promote advertisement across Canada to the general public as effective and safe.
The research has proved its efficiacy beyond doubt. More details at https://drnancymalik.wordpress.com/article/research-studies-nosodes
I urge you to think of not only health and safety of Canadian families but also economy as homeopathic medicines are comparatively cost-effective, so there is less drain on economy financially.
Thanks and Regards
Further Reading:Scientific Research in Homeopathy
Last Modified: This webpage was last updated on 13rd Feb 2014.